The first line of therapy for uncomplicated ED is oral medications such as sildenafil citrate (Viagra®), vardenafil CHI (Levitra®) and tadalafil (Cialis®). These medications – called phosphodiesterase (PDE) inhibitors - improve and prolong an erection by relaxing the muscle cells in the penis allowing for better blood flow. While PDEs are effective, a man who takes nitroglycerin for a heart condition should not use any PDE due to drug interactions that could result in a sudden drop in blood pressure.
Hormone replacement therapy
For men with low levels of testosterone, hormone replacement therapy may be beneficial for ED and increasing sexual desire. Replacement testosterone is available in skin patches and gels, injections and oral medication.
Combinations of Alprostadil including bimix and trimix are the most common medications used for self injections into the penis. The medication works to widen the blood vessels in the penis leading to an erection.
Intraurethral pellet therapy
Medicated Intraurethral Pellet Therapy (MUSE) is beneficial for men who do not respond to oral medications or who prefer not to self inject medication. Alprostadil, which is also used for penile injections, is formulated into a suppository that is inserted into the uretha.
External vacuum device
For men who prefer not to use oral medications or for men who do not respond to them, an external vacuum erection device has demonstrated success. The mechanical device causes an erection by creating a partial vacuum, which draws blood into the penis.
*Before resuming sexual activity and starting any treatment please consult your physician and/or urologist.