Research

Current Studies

Cardiac and Vascular Studies

COMMANDER
(Active/Open for Enrollment)
A Randomized, Double-blind, Event-driven, Multicenter Study Comparing the Efficacy and Safety of Rivaroxaban with Placebo for Reducing the Risk of Death, Myocardial Infarction or Stroke in Subjects with Heart Failure and Significant Coronary Artery Disease Following an Episode of Decompensated Heart Failure.

Principal Investigator: Maged Azer, MD
Co-Investigator: Lawrence Santora, MD
Sponsor: Janssen Research & Development

Ovation Prime
(Follow up/Closed for Enrollment)
A PMA Post-Approval Study to Evaluate the Long-Term Safety and effectiveness of the Ovation™/Ovation Prime™ Abdominal Stent Graft System.

Principal Investigator: Preston Flanigan, MD
Co-Investigator: Jeffrey Lawrence Ballard, MD
Co-Investigator: Stacey Tien, PA-C
Sponsor: Endologix

The LUCY Study
(Follow up/Closed for Enrollment)
TriVascular Evaluation of FemaLes who are Underrepresented Candidates for Abdominal Aortic AneurYsm Repair.

Principal Investigator: Preston Flanigan, MD
Co-Investigator: Jeffrey Lawrence Ballard, MD
Co-Investigator: Stacey Tien, PA-C
Sponsor: Endologix

Kidney Disease and Anemia

OLYMPUS
(Follow up/Closed for Enrollment)
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Roxadustat for the Treatment of Anemia in Chronic Kidney Disease Patients not on Dialysis.

Principal Investigator: Charles J. Kaupke , MD
Co-Investigator: Amer Jabara, MD
Sponsor: AstraZeneca

ROCKIES
(Active/Open for Enrollment)
A Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study of Safety and Efficacy of Roxadustat in the Treatment of Anemia in Dialysis Patients.

Principal Investigator: Charles J. Kaupke, MD
Co-Investigator: Amer Jabara, MD
Sponsor: AstraZeneca

Diabetic Neuropathy/Diabetes Mellitus

CREDENCE
(Follow up/Closed for Enrollment)
A Randomized, Double-blind, Event-driven, Placebo-controlled, Multicenter Study of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Subjects With Type 2 Diabetes Mellitus and Diabetic Nephropathy.

Principal Investigator: Charles J. Kaupke, MD
Co-Investigator: Amer Jabara, MD
Sponsor: Janssen Research & Development

Grifols GTI 1302
(Follow up/Closed for Enrollment)
A Multicenter, Randomized, Partial-Blinded, Placebo-Controlled Study to Evaluate the Safety and Efficacy of a Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects with New-Onset Type 1 Diabetes Mellitus.

Principal Investigator: Ivy-Joan Madu, MD
Co-Investigator: Samuel O. Mayeda, MD
Sponsor: Grifols Therapeutics Inc